David S. Smith

David S. Smith

Of Counsel

Pittsburgh, PA
Phone: 412.454.5862    Fax: 412.454.5060


David S. Smith, a corporate lawyer focusing on intellectual property transactions, venture financings and regulatory matters for life sciences companies and investors, is of counsel with Pepper Hamilton LLP, resident in the Pittsburgh office. Mr. Smith is a member of the firm's Health Sciences Department.

Mr. Smith’s intellectual property-related work includes IP transactions, regulatory issues and licensing. His corporate practice is concentrated in the organization, financing and growth of life sciences companies, and he is an authority on the legal issues surrounding the use of human biological materials. He frequently speaks at universities and trade conferences on commercial development of tissue, cell and stem cell technologies.

Mr. Smith is a founder and principal of Teregenics, LLC, a company formed in 2003 that provides strategic product development analysis and consulting services to institutional investors, research centers and companies participating in developing human tissue engineering and regeneration technologies.

From 2000 to 2003, Mr. Smith was senior vice president and general counsel of TissueInformatics.Inc, a bioinformatics company, until its merger with Icoria, Inc. Before that, he was of counsel at Reed Smith, LLP and led the development of that firm’s biotechnology practice in Pittsburgh.

Mr. Smith is a former adjunct professor in Carnegie Mellon University’s Department of Engineering and Public Policy and member of the Scientific Advisory Board of Clinical Cell Culture, Ltd., a tissue engineering company listed on the Australian stock exchange. He has also served as a trustee of AMD3 Education and Research Foundation, which supports the development and clinical introduction of computer assisted and minimally invasive tools and techniques for orthopedic repairs.

Mr. Smith is active in a number of trade organizations and serves on the executive committee of Tissue Engineering and Regenerative Medicine International Society. He is a past member of the board of directors of the Pennsylvania Biotechnology Association and secretary of the Pittsburgh Tissue Engineering Initiative.


  • J.D., American University Washington College of Law, 1980
  • A.B., Hamilton College, 1977

Bar Admissions

  • Pennsylvania

Practice Areas

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