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Raymond A. Miller

Raymond A. Miller is a partner in the Intellectual Property Department of Pepper Hamilton LLP, resident in the Pittsburgh office. Mr. Miller is co-chair of the firm’s Intellectual Property Transactions and Rights Management and Life Sciences practice groups, and a member of the firm’s Executive Committee.

Mr. Miller’s clients range from academic institutions to world-class medical and research facilities. His clients include physicians, venture capital groups, start-up biotechnology companies, Fortune 500 companies and the world’s leading nutritional supplement company. Mr. Miller is particularly experienced in the areas of chemistry, medicinal chemistry, genetics, pharmaceuticals, nutraceuticals, proteonomics, nanotechnology, tissue engineering, surface chemistry and cosmetics. This experience, along with Mr. Miller’s exposure to the medical fields of cardiology, neurosurgery, plastic surgery, orthopedics and tissue engineering, allow him to appreciate issues critical to Pepper’s biotechnology and life science clients.

Although Mr. Miller’s practice focuses on patent prosecution, corporate transactions involving intellectual property and strategic intellectual property counseling, he also has been involved in all facets of intellectual property. Specific examples of Mr. Miller’s experience include:

  • handling litigation, licensing and settlement negotiations based on the strengths of competing patent positions
  • preparing, filing and securing patent applications and patents throughout the world in the areas identified above
  • rendering legal opinions on issues of patentability, inventorship, ownership, infringement, invalidity, enforceability and freedom to operate
  • assisting venture capital groups and investment funds in evaluating biotechnology and life science opportunities
  • advising on the interplay of FDA and patent law on cosmetic, pharmaceutical, nutraceutical and medical device products
  • counseling drug companies on unique patent issues relating to drug development, including Orange Book listing, label claims, patent term restoration and extension, and subtle issues of written description, enablement, genus and species issues, and anticipation and obviousness in the “unpredictable arts”
  • managing diverse patent portfolios and invention disclosure programs to document and protect inventions through patent, trade secret and copyright laws
  • negotiating complex technology transfer agreements, license agreements, and asset purchase or merger agreements
  • providing patent coverage analysis for commercial products.

Mr. Miller has prepared, prosecuted, and litigated well over 100 patents. All of these were handled with the clients’ strategic and corporate goals in mind. The following select patents and publications are illustrative examples of the cross-section of Mr. Miller’s experience. Additional specific examples are available upon request.

Select Issued Patents

  • U.S. Patent No. 7,399,785, entitled “N-oxides and derivatives of melphalan for treating diseased states associated with hypoxia inducible factor”
  • U.S. Patent No. 7,381,731, entitled “Pharmaceutical composition comprising citrulline”
  • U.S. Patent No. 7,367,049, entitled “System and method for enrolling in a biometric system”
  • U.S. Patent No. 7,335,679, entitled “Wortmannin analogs and methods of using same”
  • U.S. Patent No. 7,273,708, entitled “Assays for preimplantation factor and preimplantation factor peptides”
  • U.S. Patent No. 7,242,832, entitled “Device for tissue characterization”
  • U.S. Patent No. 7,205,048, entitled “Functionalized fluorescent nanocrystal compositions and methods of making”
  • U.S. Patent No. 7,153,843, entitled “Inhibitors of phosphatidyl myo-inositol cycle”
  • U.S. Patent No. 7,148,342, entitled “Compositions and methods for sirna inhibition of angiogenesis”
  • U.S. Patent No. 7,147,917, entitled “Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media”
  • U.S. Patent No. 7,074,413, entitled “Genetically engineered rabies recombinant vaccine for immunization of stray dogs and wildlife”
  • U.S. Patent No. 7,074,175, entitled “Thermotherapy via targeted delivery of nanoscale magnetic particles”
  • U.S. Patent No. 7,056,329, entitled “Laparoscopic direct vision dissecting port”
  • U.S. Patent No. 6,004,610, entitled “Compositions of dietary fiber-rich and low-viscosity beverages”
  • U.S. Patent No. 5,998,386, entitled “Pharmaceutical compositions and method of using same for the treatment of failing myocardial tissue”
  • U.S. Patent No. 5,968,983, entitled “Method and formulation for treating vascular disease”
  • U.S. Patent No. 5,767,160, entitled “Method and formulation of stimulating nitric oxide synthesis.”
Scientific Publications
  • “Tyrosine Phosphotases: Cellular Functions and Therapeutic Potential,” Expert Opinion on Therapeutic Patents, 10(5), 675-683
  • “Effects of Farnesylcysteine Analogs on Protein Carboxyl Methylation and Signal Transduction,” The Journal of Biological Chemistry, 266, 32, 21515-21522
  • “Reversible Farnesylation of the Ras superfamily,” FASEBS, Vol. 4, No. 7, accompanied by presentation at 1990 ASBMB/AAI in New Orleans
  • “S-Farnesylcysteine Methyltransferase in Bovine Brain,” METHODS: A Companion to Methods in Enzymology, 1, 3, 283-287
  • “The Use of Alkoxy-Substituted Anomeric Radicals for the Construction of ß-Glycosides,” The Journal of the American Chemical Society, 110, 8716-8717.

Mr. Miller is a member of the American Association for the Advancement of Science, the Association of University Technology Managers, Inc. and the American Intellectual Property Law Association. He has published numerous peer-reviewed articles in academic and scientific journals.

Mr. Miller is listed in The Best Lawyers in America.

Mr. Miller is admitted to practice before the U.S. Patent & Trademark Office, the state and federal courts of Ohio and Pennsylvania, and the U.S. Court of Appeals for the Federal Circuit.

B.S. 1988 University of Akron
M.A. 1990 Princeton University
J.D. 1994 Case Western Reserve University School of Law

Bar Admissions
Admitted to practice in Pennsylvania, Ohio and before the U.S. Patent and Trademark Office

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